It really boils down to this: that all life is interrelated. We are all caught in an inescapable network of mutuality, tied to a single garment of destiny. Whatever affects one directly, affects all indirectly.
I take my guidance from the forests, who teach us something about change. The forces of creation and destruction are so tightly linked that sometimes we can't tell where one begins and the other leaves off. A long-lived overstory can dominate the forest for generations... But... something always happens that is more powerful than that overstory... A whole new ecosystem rises to replace that which no longer works in a changed world...